US President Barack Obama has said his meeting with Cuban President Raul Castro will help both countries "turn the page" after decades of hostility..
He described the meeting on the fringes of the Summit of the Americas in Panama as "candid and fruitful".
Mr Obama said that the former foes would continue to have differences but could advance mutual interests.
The meeting was the first formal talks between the two countries' leaders in more than half a century.
"What we have both concluded is that we can disagree with a spirit of respect and civility," said President Obama. "Over time, it is possible for us to turn the page and develop a new relationship between our two countries."
His remarks came at the end of a regional summit which has been dominated by the historic thaw between US-Cuba relations.